Model Number: AFP
Brand Name: Netural or OEM
Key Specifications/Special Features:
Alpha Fetoprotein (AFP)Quantitative Enzyme ImmunoassayFor in Vitro diagnostics use onlyIntended useThe Alpha Fetoprotein (AFP) Quantitative Enzyme Immunoassay is a quantitative solid phase enzyme-linkedimmunosorbent assay.
This test provides quantitative measurement of human alpha fetoprotein (AFP) antigen in human serum and in amniotic fluid.(For Professional Use Only)
Principle of the test
AFP is a glycoprotein with a molecular weight of between 65,000 and 70,000 Daltons including 4% of carbohydrateduring fetal development, AFP maintains high levels in the serum and drops to very low levels throughout the remainder of life. AFP is elevated in the malignant diseases of hepatocellular, testicular nonseminomatous origin, and occasionally of other endodermis originAFP may be slightly elevated or persisted in the patients with large hepatic metastases or viral hepatitis.
AFP measurement is widely accepted as tumor marker and for monitoring.
The therapeutic effectiveness of hepatocellularcancer and non-seminomatous testicular cancer.
The highest AFP concentration appears in the amniotic fluid in the earliest stages of pregnancy, and diminishes in concentration through the remainder of the pregnancy. Elevated AFP levels in the amniotic fluid were found in fetus with open neural tube defects, e. g. spinal bifida or anencephalyalso were found in fetus with severe fetal hemolytic disease, omphalocele, esophageal atresia, congenital nephrosis, intrauterine death, or fetal bleeding into the amniotic fluid. For diagnostic purpose, ultrasonography and acetylcholinesterase measurement should be performed in conjunction with the measurement of AFP.
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